EC |
1.1.2.3 |
Accepted name: |
L-lactate dehydrogenase (cytochrome) |
Reaction: |
(S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H+ |
Other name(s): |
lactic acid dehydrogenase; cytochrome b2 (flavin-free derivative of flavocytochrome b2); flavocytochrome b2; L-lactate cytochrome c reductase; L(+)-lactate:cytochrome c oxidoreductase; dehydrogenase, lactate (cytochrome); L-lactate cytochrome c oxidoreductase; lactate dehydrogenase (cytochrome); lactic cytochrome c reductase |
Systematic name: |
(S)-lactate:ferricytochrome-c 2-oxidoreductase |
Comments: |
Identical with cytochrome b2; a flavohemoprotein (FMN). |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9078-32-4 |
References: |
1. |
Appleby, C.A. and Morton, R.K. Lactic dehydrogenase and cytochrome b2 of baker's yeast. Purification and crystallization. Biochem. J. 71 (1959) 492–499. [PMID: 13638255] |
2. |
Appleby, C.A. and Morton, R.K. Lactic dehydrogenase and cytochrome b2 of baker's yeast. Enzymic and chemical properties of the crystalline enzyme. Biochem. J. 73 (1959) 539–550. [PMID: 13793977] |
3. |
Bach, S.G., Dixon, M. and Zerfas, L.G. Yeast lactic dehydrogenase and cytochrome b2. Biochem. J. 40 (1946) 229–239. [PMID: 16747991] |
4. |
Nygaard, A.P. Lactate dehydrogenases of yeast. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Ed.), The Enzymes, 2nd edn, vol. 7, Academic Press, New York, 1963, pp. 557–565. |
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[EC 1.1.2.3 created 1961] |
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