ExplorEnz: EC 1.1.3.38

1.1.3.38

Accepted name:

vanillyl-alcohol oxidase

Reaction:

vanillyl alcohol + O₂ = vanillin + H₂O₂

Other name(s):

4-hydroxy-2-methoxybenzyl alcohol oxidase

Systematic name:

vanillyl alcohol:oxygen oxidoreductase

Comments:

Vanillyl-alcohol oxidase from Penicillium simplicissimum contains covalently bound FAD. It converts a wide range of 4-hydroxybenzyl alcohols and 4-hydroxybenzylamines into the corresponding aldehydes. The allyl group of 4-allylphenols is also converted into the -CH=CH-CH₂OH group.

References:

1.	de Jong, E., van Berkel, W.J.H., van der Zwan, R.P. and de Bont, J.A.M. Purification and characterization of vanillyl-alcohol oxidase from Penicillium simplicissimum, a novel aromatic alcohol oxidase containing covalently bound FAD. Eur. J. Biochem. 208 (1992) 651–657. [PMID: 1396672]
2.	Fraaije, M.W., Veeger, C. and van Berkel, W.J.H. Substrate specificity of flavin-dependent vanillyl-alcohol oxidase from Penicillium simplicissimum. Evidence for the production of 4-hydroxycinnamyl alcohols from 4-allylphenols. Eur. J. Biochem. 234 (1995) 271–277. [PMID: 8529652]

[EC 1.1.3.38 created 1999]