The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.1.3.49     
Accepted name: (R)-mandelonitrile oxidase
Reaction: (R)-mandelonitrile + O2 = benzoyl cyanide + H2O2
Glossary: (R)-mandelonitrile = (R)-2-hydroxy-2-phenylacetonitrile
Other name(s): ChuaMOX (gene name)
Systematic name: (R)-mandelonitrile:oxygen oxidoreductase
Comments: Contains FAD. The enzyme, characterized from the millipede Chamberlinius hualienensis, is segregated from its substrate, which is contained in special sacs. The sacs are ruptured during defensive behavior, allowing the enzyme and substrate to mix in special reaction chambers leading to production of the defensive chemical benzoyl cyanide.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Ishida, Y., Kuwahara, Y., Dadashipour, M., Ina, A., Yamaguchi, T., Morita, M., Ichiki, Y. and Asano, Y. A sacrificial millipede altruistically protects its swarm using a drone blood enzyme, mandelonitrile oxidase. Sci. Rep. 6:26998 (2016). [DOI] [PMID: 27265180]
[EC 1.1.3.49 created 2016]
 
 


Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald