| EC |
1.1.3.50 |
| Accepted name: |
C-glycoside oxidase |
| Reaction: |
carminate + O2 = 3′-dehydrocarminate + H2O2 |
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For diagram of carminate catabolism, click here |
| Glossary: |
carminate = 7-(β-D-glucopyranosyl)-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-9,10-dihydroanthracene-2-carboxylate |
| Other name(s): |
carA (gene name) |
| Systematic name: |
carminate:oxygen 3′-oxidoreductase (H2O2-forming) |
| Comments: |
A flavoprotein (FAD). This bacterial enzyme participates in degradation of certain C-glucosides by catalysing the oxidation of the hydroxyl group at position 3 of the glycose moiety. The enzyme was found active with assorted C-glycosides, such as carminate, mangiferin, and C6-glycosylated flavonoids, but not with D-glucose or C8-glycosylated flavonoids. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Kumano, T., Hori, S., Watanabe, S., Terashita, Y., Yu, H.Y., Hashimoto, Y., Senda, T., Senda, M. and Kobayashi, M. FAD-dependent C-glycoside-metabolizing enzymes in microorganisms: Screening, characterization, and crystal structure analysis. Proc. Natl. Acad. Sci. USA 118(40) (2021) e2106580118. [DOI] [PMID: 34583991] |
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| [EC 1.1.3.50 created 2022] |
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