EC |
1.1.99.32 |
Accepted name: |
L-sorbose 1-dehydrogenase |
Reaction: |
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor |
Glossary: |
1-dehydro-L-sorbose = L-sorbosone = 2-dehydro-L-gulose |
Other name(s): |
SDH (ambiguous) |
Systematic name: |
L-sorbose:acceptor 1-oxidoreductase |
Comments: |
The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
References: |
1. |
Sugisawa, T., Hoshino, T., Nomura, S. and Fujiwara, A. Isolation and characterization of membrane-bound L-sorbose dehydrogenase from Gluconobacter melanogenus UV10. Agric. Biol. Chem. 55 (1991) 363–370. |
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[EC 1.1.99.32 created 2008] |
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