| EC |
1.12.99.6 |
| Accepted name: |
hydrogenase (acceptor) |
| Reaction: |
H2 + acceptor = reduced acceptor |
| Other name(s): |
H2 producing hydrogenase (ambiguous); hydrogen-lyase (ambiguous); hydrogenlyase (ambiguous); uptake hydrogenase (ambiguous); hydrogen:(acceptor) oxidoreductase |
| Systematic name: |
hydrogen:acceptor oxidoreductase |
| Comments: |
Uses molecular hydrogen for the reduction of a variety of substances. Contains iron-sulfur clusters. The enzyme from some sources contains nickel. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9027-05-8 |
| References: |
| 1. |
Shug, A.L., Wilson, P.W., Green, D.E. and Mahler, H.R. The role of molybdenum and flavin in hydrogenase. J. Am. Chem. Soc. 76 (1954) 3355–3356. |
| 2. |
Adams, M.W.W., Mortenson, L.E. and Chen, J.-S. Hydrogenase. Biochim. Biophys. Acta 594 (1981) 105–176. [PMID: 6786341] |
| 3. |
Vignais, P.M., Billoud, B. and Meyer, J. Classification and phylogeny of hydrogenases. FEMS Microbiol. Rev. 25 (2001) 455–501. [DOI] [PMID: 11524134] |
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| [EC 1.12.99.6 created 2002, modified 2003] |
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