EC |
1.13.11.6 |
Accepted name: |
3-hydroxyanthranilate 3,4-dioxygenase |
Reaction: |
3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde |
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For diagram of tryptophan catabolism, click here |
Other name(s): |
3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid oxygenase; 3-hydroxyanthranilic oxygenase; 3-hydroxyanthranilic acid oxidase; 3HAO; 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) |
Systematic name: |
3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (ring-opening) |
Comments: |
Requires Fe2+. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9029-50-9 |
References: |
1. |
Decker, R.H., Kang, H.H., Leach, F.R. and Henderson, L.M. Purification and properties of 3-hydroxyanthranilic acid oxidase. J. Biol. Chem. 236 (1961) 3076–3082. [PMID: 13884755] |
2. |
Hayaishi, O. Direct oxygenation by O2, oxygenases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Ed.), The Enzymes, 2nd edn, vol. 8, Academic Press, New York, 1963, pp. 353–371. |
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[EC 1.13.11.6 created 1965 as EC 1.13.1.6, transferred 1972 to EC 1.13.11.6] |
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