| EC |
1.13.11.67 |
| Accepted name: |
8′-apo-β-carotenoid 14′,13′-cleaving dioxygenase |
| Reaction: |
8′-apo-β-carotenol + O2 = 14′-apo-β-carotenal + an uncharacterized product |
|
For diagram of 8′-apo-β-carotenal metabolites, click here |
| Other name(s): |
8′-apo-β-carotenol:O2 oxidoreductase (14′,13′-cleaving) |
| Systematic name: |
8′-apo-β-carotenol:oxygen oxidoreductase (14′,13′-cleaving) |
| Comments: |
A thiol-dependent enzyme isolated from rat and rabbit. Unlike EC 1.13.11.63, β-carotene-15,15′-dioxygenase, it is not active towards β-carotene. The secondary product has not been characterized, but may be (3E,5E)-7-hydroxy-6-methylhepta-3,5-dien-2-one. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 198028-39-6 |
| References: |
| 1. |
Dmitrovskii, A.A., Gessler, N.N., Gomboeva, S.B., Ershov, Yu.V. and Bykhovsky, V.Ya. Enzymatic oxidation of β-apo-8′-carotenol to β-apo-14′-carotenal by an enzyme different from β-carotene-15,15′-dioxygenase. Biochemistry (Mosc.) 62 (1997) 787–792. [PMID: 9331970] |
|
| [EC 1.13.11.67 created 2000 as EC 1.13.12.12, transferred 2012 to EC 1.13.11.67] |
| |
|
| |
|
Printable version