ExplorEnz: EC 1.13.11.78

Your query returned 1 entry. Printable version

1.13.11.78

Accepted name:

2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)

Reaction:

(2-amino-1-hydroxyethyl)phosphonate + O₂ = glycine + phosphate

Other name(s):

phnZ (gene name)

Systematic name:

2-amino-1-hydroxyethylphosphonate:oxygen 1-oxidoreductase (glycine-forming)

Comments:

Requires Fe²⁺. The enzyme, characterized from a marine bacterium, is involved in a 2-aminoethylphosphonate degradation pathway.

Links to other databases:

BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB

References:

1.	McSorley, F.R., Wyatt, P.B., Martinez, A., DeLong, E.F., Hove-Jensen, B. and Zechel, D.L. PhnY and PhnZ comprise a new oxidative pathway for enzymatic cleavage of a carbon-phosphorus bond. J. Am. Chem. Soc. 134 (2012) 8364–8367. [DOI] [PMID: 22564006]
2.	Worsdorfer, B., Lingaraju, M., Yennawar, N.H., Boal, A.K., Krebs, C., Bollinger, J.M., Jr. and Pandelia, M.E. Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases. Proc. Natl. Acad. Sci. USA 110 (2013) 18874–18879. [DOI] [PMID: 24198335]

[EC 1.13.11.78 created 2014]