ExplorEnz: EC 1.13.11.83

Your query returned 1 entry. Printable version

1.13.11.83

Accepted name:

4-hydroxy-3-prenylphenylpyruvate oxygenase

Reaction:

3-(4-hydroxy-3-prenylphenyl)pyruvate + O₂ = 4-hydroxy-3-prenylmandelate + CO₂

For diagram of 3-dimethylallyl-4-hydroxybenzoate biosynthesis, click here

Glossary:

3-(4-hydroxy-3-prenylphenyl)pyruvate = 3-(4-hydroxy-3-prenylphenyl)-2-oxopropanoate
4-hydroxy-3-prenylmandelate = 2-hydroxy-2-(4-hydroxy-3-prenylphenyl)acetate
prenyl = 3-methylbut-2-en-1-yl

Other name(s):

CloR

Systematic name:

3-(4-hydroxy-3-prenylphenyl)pyruvate:oxygen 1,2-oxidoreductase (4-hydroxy-3-prenylmandelate-forming)

Comments:

Requires non-heme-iron(II). Isolated from the bacterium Streptomyces roseochromogenes DS 12976. A bifunctional enzyme involved in clorobiocin biosynthesis that also catalyses the activity of EC 1.13.12.23, 4-hydroxy-3-prenylbenzoate synthase.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Pojer, F., Kahlich, R., Kammerer, B., Li, S.M. and Heide, L. CloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesis. J. Biol. Chem. 278 (2003) 30661–30668. [DOI] [PMID: 12777382]

[EC 1.13.11.83 created 2017]