The Enzyme Database

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Accepted name: Oplophorus-luciferin 2-monooxygenase
Reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 +
For diagram of reaction, click here
Glossary: Oplophorus luciferin = 8-benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one
Other name(s): Oplophorus luciferase
Systematic name: Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating)
Comments: The luciferase from the deep sea shrimp Oplophorus gracilirostris is a complex composed of more than one protein. The enzyme’s specificity is quite broad, with both coelenterazine and bisdeoxycoelenterazine being good substrates.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Shimomura, O., Masugi, T., Johnson, F.H. and Haneda, Y. Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris. Biochemistry 17 (1978) 994–998. [PMID: 629957]
2.  Inouye, S., Watanabe, K., Nakamura, H., Shimomura, O. Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase. FEBS Lett. 481 (2000) 19–25. [DOI] [PMID: 10984608]
[EC created 2004]

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