| EC |
1.14.11.56 |
| Accepted name: |
L-proline cis-4-hydroxylase |
| Reaction: |
L-proline + 2-oxoglutarate + O2 = cis-4-hydroxy-L-proline + succinate + CO2 |
| Systematic name: |
L-proline,2-oxoglutarate:oxygen oxidoreductase (cis-4-hydroxylating) |
| Comments: |
Requires Fe2+ and ascorbate. The enzyme, isolated from Rhizobium species, only produces cis-4-hydroxy-L-proline (cf. EC 1.14.11.57, L-proline trans-4-hydroxylase). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Hara, R. and Kino, K. Characterization of novel 2-oxoglutarate dependent dioxygenases converting L-proline to cis-4-hydroxy-L-proline. Biochem. Biophys. Res. Commun. 379 (2009) 882–886. [DOI] [PMID: 19133227] |
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| [EC 1.14.11.56 created 2017] |
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