| EC |
1.14.11.75 |
| Accepted name: |
31-hydroxy-L-isoleucine 4-dioxygenase |
| Reaction: |
31-hydroxy-L-isoleucine + 2-oxoglutarate + O2 = (4S)-31,4-dihydroxy-L-isoleucine + succinate + CO2 |
| Other name(s): |
hilB (gene name); 4′-hydroxy-L-isoleucine 4-dioxygenase (incorrect) |
| Systematic name: |
31-hydroxy-L-isoleucine,2-oxoglutarate:oxygen oxidoreductase (4S-hydroxylating) |
| Comments: |
Requires Fe2+ and ascorbate. The enzyme has been characterized from the bacterium Pantoea ananatis. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Smirnov, S.V., Sokolov, P.M., Kotlyarova, V.A., Samsonova, N.N., Kodera, T., Sugiyama, M., Torii, T., Hibi, M., Shimizu, S., Yokozeki, K. and Ogawa, J. A novel L-isoleucine-4′-dioxygenase and L-isoleucine dihydroxylation cascade in Pantoea ananatis. MicrobiologyOpen 2 (2013) 471–481. [PMID: 23554367] |
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| [EC 1.14.11.75 created 2020] |
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