| EC |
1.14.12.10 |
| Accepted name: |
benzoate 1,2-dioxygenase |
| Reaction: |
benzoate + NADH + H+ + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ |
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For diagram of benzoate metabolism, click here and for diagram of reaction, click here |
| Other name(s): |
benzoate hydroxylase; benzoate hydroxylase; benzoic hydroxylase; benzoate dioxygenase; benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating) [incorrect] |
| Systematic name: |
benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating) |
| Comments: |
A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase. Requires Fe2+. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9059-18-1 |
| References: |
| 1. |
Yamaguchi, M. and Fujisawa, H. Characterization of NADH-cytochrome c reductase, a component of benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1. J. Biol. Chem. 253 (1978) 8848–8853. [PMID: 214433] |
| 2. |
Yamaguchi, M. and Fujisawa, H. Purification and characterization of an oxygenase component in benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1. J. Biol. Chem. 255 (1980) 5058–5063. [PMID: 7372624] |
| 3. |
Yamaguchi, M. and Fujisawa, H. Subunit structure of oxygenase component in benzoate-1,2-dioxygenase system from Pseudomonas arvilla C-1. J. Biol. Chem. 257 (1982) 12497–12502. [PMID: 7130163] |
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| [EC 1.14.12.10 created 1972 as EC 1.13.99.2, transferred 1992 to EC 1.14.12.10] |
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