| EC |
1.14.13.131 |
| Accepted name: |
dissimilatory dimethyl sulfide monooxygenase |
| Reaction: |
dimethyl sulfide + O2 + NADH + H+ = methanethiol + formaldehyde + NAD+ + H2O |
|
For diagram of dimethyl sulfide catabolism, click here |
| Other name(s): |
dmoAB (gene names); dimethyl sulfide C-monooxygenase; dimethylsulfide monooxygenase (ambiguous); dimethyl sulfide monooxygenase (ambiguous) |
| Systematic name: |
dimethyl sulfide,NADH:oxygen oxidoreductase |
| Comments: |
The enzyme participates exclusively in sulfur dissimilation. It has lower activity with diethyl sulfide and other short-chain alkyl methyl sulfides. Its activity is stimulated by combined addition of FMN, and, after depletion of cations, of Mg2+ and Fe2+. The enzymes from bacteria of the Hyphomicrobium genus are a two component system that includes an FMN-dependent reductase subunit and a monooxygenase subunit. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
De Bont, J.A.M., Van Dijken, J.P. and Harder, W. Dimethyl sulphoxide and dimethyl sulphide as a carbon, sulphur and energy source for growth of Hyphomicrobium S. J. Gen. Microbiol. 127 (1981) 315–323. |
| 2. |
Boden, R., Borodina, E., Wood, A.P., Kelly, D.P., Murrell, J.C. and Schafer, H. Purification and characterization of dimethylsulfide monooxygenase from Hyphomicrobium sulfonivorans. J. Bacteriol. 193 (2011) 1250–1258. [DOI] [PMID: 21216999] |
|
| [EC 1.14.13.131 created 2011] |
| |
|
| |
|
Printable version