| EC |
1.14.13.189 |
| Accepted name: |
5-methyl-1-naphthoate 3-hydroxylase |
| Reaction: |
5-methyl-1-naphthoate + NADPH + H+ + O2 = 3-hydroxy-5-methyl-1-naphthoate + NADP+ + H2O
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For diagram of the azinomycin biosynthesis (part of pathway), click here |
| Other name(s): |
AziB1 |
| Systematic name: |
5-methyl-1-naphthoate,NADPH:oxygen oxidoreductase (3-hydroxylating) |
| Comments: |
The enzyme from the bacterium Streptomyces sahachiroi is involved in the biosynthesis of 3-methoxy-5-methyl-1-naphthoate, a component of of the the antitumor antibiotic azinomycin B. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Ding, W., Deng, W., Tang, M., Zhang, Q., Tang, G., Bi, Y. and Liu, W. Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B. Mol. Biosyst. 6 (2010) 1071–1081. [DOI] [PMID: 20485749] |
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| [EC 1.14.13.189 created 2014] |
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