ExplorEnz: EC 1.14.13.209

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1.14.13.209

Accepted name:

salicyloyl-CoA 5-hydroxylase

Reaction:

2-hydroxybenzoyl-CoA + NADH + H⁺ + O₂ = gentisyl-CoA + NAD⁺ + H₂O

Glossary:

2-hydroxybenzoyl-CoA = salicyloyl-CoA
gentisate = 2,5-dihydroxybenzoate

Other name(s):

sdgC (gene name)

Systematic name:

salicyloyl-CoA,NADH:oxygen oxidoreductase (5-hydroxylating)

Comments:

The enzyme, characterized from the bacterium Streptomyces sp. WA46, participates in a pathway for salicylate degradation. cf. EC 1.14.13.172, salicylate 5-hydroxylase.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Ishiyama, D., Vujaklija, D. and Davies, J. Novel pathway of salicylate degradation by Streptomyces sp. strain WA46. Appl. Environ. Microbiol. 70 (2004) 1297–1306. [DOI] [PMID: 15006746]

[EC 1.14.13.209 created 2015]