| EC |
1.14.13.237 |
| Accepted name: |
aliphatic glucosinolate S-oxygenase |
| Reaction: |
an ω-(methylsulfanyl)alkyl-glucosinolate + NADPH + H+ + O2 = an ω-(methylsulfinyl)alkyl-glucosinolate + NADP+ + H2O |
| Glossary: |
ω-(methylsulfanyl)alkyl-glucosinolate = an ω-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside |
| Other name(s): |
ω-(methylthio)alkylglucosinolate S-oxygenase; GS-OX1 (gene name); ω-(methylthio)alkyl-glucosinolate,NADPH:oxygen S-oxidoreductase |
| Systematic name: |
ω-(methylsulfanyl)alkyl-glucosinolate,NADPH:oxygen S-oxidoreductase |
| Comments: |
The enzyme is a member of the flavin-dependent monooxygenase (FMO) family (cf. EC 1.14.13.8). The plant Arabidopsis thaliana contains five isoforms. GS-OX1 through GS-OX4 are able to catalyse the S-oxygenation independent of chain length, while GS-OX5 is specific for 8-(methylsulfanyl)octyl glucosinolate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Hansen, B.G., Kliebenstein, D.J. and Halkier, B.A. Identification of a flavin-monooxygenase as the S-oxygenating enzyme in aliphatic glucosinolate biosynthesis in Arabidopsis. Plant J. 50 (2007) 902–910. [DOI] [PMID: 17461789] |
| 2. |
Li, J., Hansen, B.G., Ober, J.A., Kliebenstein, D.J. and Halkier, B.A. Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis. Plant Physiol. 148 (2008) 1721–1733. [DOI] [PMID: 18799661] |
|
| [EC 1.14.13.237 created 2017] |
| |
|
| |
|
Printable version