| EC |
1.14.13.4 |
| Accepted name: |
melilotate 3-monooxygenase |
| Reaction: |
3-(2-hydroxyphenyl)propanoate + NADH + H+ + O2 = 3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O |
| Other name(s): |
2-hydroxyphenylpropionate hydroxylase; melilotate hydroxylase; 2-hydroxyphenylpropionic hydroxylase; melilotic hydroxylase |
| Systematic name: |
3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating) |
| Comments: |
A flavoprotein (FAD). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37256-72-7 |
| References: |
| 1. |
Levy, C.C. Melilotate hydroxylase. Purification of the enzyme and the nature of the prosthetic group. J. Biol. Chem. 242 (1967) 747–753. [PMID: 6017743] |
| 2. |
Levy, C.C. and Frost, P. The metabolism of coumarin by a microorganism. V. Melilotate hydroxylase. J. Biol. Chem. 241 (1966) 997–1003. [PMID: 4285850] |
| 3. |
Strickland, S. and Massey, V. The purification and properties of the flavoprotein melilotate hydroxylase. J. Biol. Chem. 248 (1973) 2944–2952. [PMID: 4348920] |
| 4. |
Strickland, S. and Massey, V. The mechanism of action of the flavoprotein melilotate hydroxylase. J. Biol. Chem. 248 (1973) 2953–2962. [PMID: 4348921] |
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| [EC 1.14.13.4 created 1972] |
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