| EC |
1.14.13.63 |
| Accepted name: |
3-hydroxyphenylacetate 6-hydroxylase |
| Reaction: |
3-hydroxyphenylacetate + NAD(P)H + H+ + O2 = 2,5-dihydroxyphenylacetate + NAD(P)+ + H2O |
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For diagram of the homogentisate pathways, click here |
| Glossary: |
homogentisate = 2,5-dihydroxyphenylacetate |
| Other name(s): |
3-hydroxyphenylacetate 6-monooxygenase |
| Systematic name: |
3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating) |
| Comments: |
3-hydroxyphenylacetate 6-hydroxylase from Flavobacterium sp. is highly specific for 3-hydroxyphenylacetate and uses NADH and NADPH as electron donors with similar efficiency. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 114705-01-0 |
| References: |
| 1. |
van Berkel, W.H.J. and van den Tweel, W.J.J. Purification and characterisation of 3-hydroxyphenylacetate 6-hydroxylase: a novel FAD-dependent monooxygenase from a Flavobacterium sp. Eur. J. Biochem. 201 (1991) 585–592. [DOI] [PMID: 1935954] |
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| [EC 1.14.13.63 created 1999] |
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