| EC |
1.14.13.64 |
| Accepted name: |
4-hydroxybenzoate 1-hydroxylase |
| Reaction: |
4-hydroxybenzoate + NAD(P)H + 2 H+ + O2 = hydroquinone + NAD(P)+ + H2O + CO2 |
| Other name(s): |
4-hydroxybenzoate 1-monooxygenase |
| Systematic name: |
4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating) |
| Comments: |
Requires FAD. The enzyme from Candida parapsilosis is specific for 4-hydroxybenzoate derivatives and prefers NADH to NADPH as electron donor. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, CAS registry number: 134214-78-1 |
| References: |
| 1. |
van Berkel, W.J.H., Eppink, M.H.M., Middelhoven, W.J., Vervoort, J. and Rietjens, I.M.C.M. Catabolism of 4-hydroxybenzoate in Candida parapsilosis proceeds through initial oxidative decarboxylation by a FAD-dependent 4-hydroxybenzoate 1-hydroxylase. FEMS Microbiol. Lett. 121 (1994) 207–216. [DOI] [PMID: 7926672] |
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| [EC 1.14.13.64 created 1999] |
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