| EC |
1.14.14.100 |
| Accepted name: |
dihydrosanguinarine 10-monooxygenase |
| Reaction: |
dihydrosanguinarine + [reduced NADPH—hemoprotein reductase] + O2 = 10-hydroxydihydrosanguinarine + [oxidized NADPH—hemoprotein reductase] + H2O |
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For diagram of chelirubine, macarpine and sanguinarine biosynthesis, click here |
| Other name(s): |
dihydrosanguinarine 10-hydroxylase |
| Systematic name: |
dihydrosanguinarine,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (10-hydroxylating) |
| Comments: |
A cytochrome P-450 (heme-thiolate) protein involved in benzophenanthridine alkaloid synthesis in higher plants. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 144388-41-0 |
| References: |
| 1. |
De-Eknamkul, W., Tanahashi, T. and Zenk, M.H. Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia. Phytochemistry 31 (1992) 2713–2717. |
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| [EC 1.14.14.100 created 1999 as EC 1.14.13.56, transferred 2018 to EC 1.14.14.100] |
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