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Your query returned 1 entry. 
Printable version
| EC | 1.14.14.161 | ||
| Accepted name: | nepetalactol monooxygenase | ||
| Reaction: | (+)-cis,trans-nepetalactol + 3 [reduced NADPH—hemoprotein reductase] + 3 O2 = 7-deoxyloganetate + 3 [oxidized NADPH—hemoprotein reductase] + 4 H2O (overall reaction) (1a) (+)-cis,trans-nepetalactol + [reduced NADPH—hemoprotein reductase] + O2 = 7-deoxyloganetic alcohol + [oxidized NADPH—hemoprotein reductase] + H2O (1b) 7-deoxyloganetic alcohol + [reduced NADPH—hemoprotein reductase] + O2 = iridotrial + [oxidized NADPH—hemoprotein reductase] + 2 H2O (1c) iridotrial + [reduced NADPH—hemoprotein reductase] + O2 = 7-deoxyloganetate + [oxidized NADPH—hemoprotein reductase] + H2O |
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| For diagram of gibberellin A12 biosynthesis, click here | |||
| Glossary: | (+)-cis,trans-nepetalactol = (4aS,7S,7aR)-4,7-dimethyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-ol 7-deoxyloganetate = (1S,4aS,7S,7aR)-1-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate |
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| Other name(s): | CYP76A26 (gene name); iridoid oxidase (misleading) | ||
| Systematic name: | (+)-cis,trans-nepetalactol,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (hydroxylating) | ||
| Comments: | The enzyme, characterized from the plant Catharanthus roseus, is a cytochrome P-450 (heme thiolate) protein. It catalyses three successive reactions in the pathway leading to biosynthesis of monoterpenoid indole alkaloids. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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