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Your query returned 1 entry. Printable version
EC | 1.14.14.170 | ||
Accepted name: | 8-epi-inunolide synthase | ||
Reaction: | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH—hemoprotein reductase] + O2 = 8-epi-inunolide + [oxidized NADPH—hemoprotein reductase] + 2 H2O (overall reaction) (1a) germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH—hemoprotein reductase] + O2 = 8α-hydroxygermacra-1(10),4,11(13)-trien-12-oate + [oxidized NADPH—hemoprotein reductase] + H2O (1b) 8α-hydroxygermacra-1(10),4,11(13)-trien-12-oate = 8-epi-inunolide + H2O (spontaneous) |
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For diagram of costunolide, eupatolide and 8-epi-inunolide biosynthesis, click here | |||
Glossary: | 8-epi-inunolide = germacra-1(10),4,11(13)-trien-12,8α-lactone | ||
Other name(s): | CYP71BL1 | ||
Systematic name: | germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (8α-hydroxylating) | ||
Comments: | A cytochrome P-450 (heme-thiolate) protein from the plant Inula hupehensis. The enzyme also produces 8β-hydroxygermacra-1(10),4,11(13)-triene-12-oate (EC 1.14.14.168, germacrene A acid 8β-hydroxylase). | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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