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Your query returned 1 entry. 
Printable version
| EC | 1.14.14.42 | ||||
| Accepted name: | homomethionine N-monooxygenase | ||||
| Reaction: | an L-polyhomomethionine + 2 [reduced NADPH—hemoprotein reductase] + 2 O2 = an (E)-ω-(methylsulfanyl)alkanal oxime + 2 [oxidized NADPH—hemoprotein reductase] + CO2 + 3 H2O (overall reaction) (1a) an L-polyhomomethionine + [reduced NADPH—hemoprotein reductase] + O2 = an L-N-hydroxypolyhomomethionine + [oxidized NADPH—hemoprotein reductase] + H2O (1b) an L-N-hydroxypolyhomomethionine + [reduced NADPH—hemoprotein reductase] + O2 = an L-N,N-dihydroxypolyhomomethionine + [oxidized NADPH—hemoprotein reductase] + H2O (1c) an L-N,N-dihydroxypolyhomomethionine = an (E)-ω-(methylsulfanyl)alkanal oxime + CO2 + H2O |
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| Glossary: | homomethionine = (2S)-2-amino-5-(methylsulfanyl)pentanoate an L-polyhomomethionine = analogs of L-methionine that contain additional methylene groups in the side chain prior to the sulfur atom. |
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| Other name(s): | CYP79F1 (gene name); CYP79F2 (gene name) | ||||
| Systematic name: | L-polyhomomethionine,[NADPH—hemoprotein reductase]:oxygen oxidoreductase | ||||
| Comments: | This plant cytochrome P-450 (heme thiolate) enzyme is involved in methionine-derived aliphatic glucosinolates biosynthesis. It catalyses two successive N-hydroxylations, which are followed by dehydration and decarboxylation. CYP79F1 from Arabidopsis thaliana can metabolize mono-, di-, tri-, tetra-, penta-, and hexahomomethionine to their corresponding aldoximes, while CYP79F2 from the same plant can only metabolize penta- and hexahomomethionine. | ||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
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