EC |
1.14.14.72 |
Accepted name: |
drimenol monooxygenase |
Reaction: |
drimenol + [reduced NADPH—hemoprotein reductase] + O2 = drimendiol + [oxidized NADPH—hemoprotein reductase] + H2O |
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For diagram of podophyllotoxin biosynthesis, click here and for diagram of drimenol metabolites, click here |
Glossary: |
drimendiol = drim-7-ene-11,12-diol |
Other name(s): |
PhDOX1 |
Systematic name: |
drimenol,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (drimendiol-forming) |
Comments: |
A cytochrome P-450 (heme-thiolate) protein isolated from the plant Persicaria hydropiper (water pepper). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Henquet, M.GL., Prota, N., van der Hooft, J.JJ., Varbanova-Herde, M., Hulzink, R.JM., de Vos, M., Prins, M., de Both, M.TJ., Franssen, M.CR., Bouwmeester, H. and Jongsma, M. Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes. Plant J. 90 (2017) 1052–1063. [DOI] [PMID: 28258968] |
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[EC 1.14.14.72 created 2018] |
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