|
|
Your query returned 1 entry. 
Printable version
| EC | 1.14.14.79 | ||
| Accepted name: | docosahexaenoic acid ω-hydroxylase | ||
| Reaction: | docosahexaenoate + [reduced NADPH—hemoprotein reductase] + O2 = 22-hydroxydocosahexaenoate + [oxidized NADPH—hemoprotein reductase] + H2O | ||
| Glossary: | docosahexaenoate = (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate icosapentaenoate = (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate |
||
| Other name(s): | CYP4F3B; CYP4V2; docosahexaenoate,NADPH:O2 oxidoreductase (22-hydroxydocosahexaenoate forming) | ||
| Systematic name: | docosahexaenoate,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (22-hydroxydocosahexaenoate-forming) | ||
| Comments: | A cytochrome P-450 (heme-thiolate) protein isolated from human eye tissue. Defects in the enzyme are associated with Bietti crystalline corneoretinal dystrophy. The enzyme also produces some 21-hydroxydocosahexaenoate. Acts in a similar way on icosapentaenoic acid. | ||
| Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc | ||
| References: |
| ||