The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: 3,9-dihydroxypterocarpan 6a-monooxygenase
Reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + [reduced NADPH—hemoprotein reductase] + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + [oxidized NADPH—hemoprotein reductase] + H2O
For diagram of glyceollin biosynthesis (part 2), click here
Other name(s): 3,9-dihydroxypterocarpan 6a-hydroxylase; 3,9-dihydroxypterocarpan 6α-monooxygenase (erroneous); CYP93A1 (gene name)
Systematic name: (6aR,11aR)-3,9-dihydroxypterocarpan,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (6a-hydroxylating)
Comments: A cytochrome P-450 (heme-thiolate) protein found in soybean. The product of the reaction is the biosynthetic precursor of the glyceollin phytoalexins.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 92584-16-2
1.  Hagmann, M.-L., Heller, W. and Grisebach, H. Induction of phytoalexin synthesis in soybean. Stereospecific 3,9-dihydroxypterocarpan 6a-hydroxylase from elicitor-induced soybean cell cultures. Eur. J. Biochem. 142 (1984) 127–131. [DOI] [PMID: 6540173]
2.  Schopfer, C.R., Kochs, G., Lottspeich, F. and Ebel, J. Molecular characterization and functional expression of dihydroxypterocarpan 6a-hydroxylase, an enzyme specific for pterocarpanoid phytoalexin biosynthesis in soybean (Glycine max L.). FEBS Lett. 432 (1998) 182–186. [PMID: 9720921]
[EC created 1989 as EC, transferred 2018 to EC]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald