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Your query returned 1 entry. 
Printable version
| EC | 1.14.14.97 | ||||
| Accepted name: | methyltetrahydroprotoberberine 14-monooxygenase | ||||
| Reaction: | (1) (S)-cis-N-methylcanadine + [reduced NADPH—hemoprotein reductase] + O2 = allocryptopine + [oxidized NADPH—hemoprotein reductase] + H2O (2) (S)-cis-N-methylstylopine + [reduced NADPH—hemoprotein reductase] + O2 = protopine + [oxidized NADPH—hemoprotein reductase] + H2O |
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| For diagram of canadine biosynthesis, click here and for diagram of stylopine biosynthesis, click here | |||||
| Other name(s): | methyltetrahydroprotoberberine 14-hydroxylase; (S)-cis-N-methyltetrahydroberberine 14-monooxygenase; (S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase; CYP82N4 (gene name); (S)-N-methylcanadine,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating); (S)-cis-N-methylstylopine 14-hydroxylase | ||||
| Systematic name: | (S)-cis-N-methylcanadine,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating) | ||||
| Comments: | A cytochrome P-450 (heme-thiolate) protein involved in the biosynthesis of isoquinoline alkaloids in plants. It also hydroxylates (S)-cis-N-methyltetrahydrothalifendine, and (S)-cis-N-methyltetrahydropalmatine. | ||||
| Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 113478-42-5 | ||||
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