|
Your query returned 1 entry. Printable version
EC | 1.14.20.4 | ||||||||||
Accepted name: | anthocyanidin synthase | ||||||||||
Reaction: | a (2R,3S,4S)-leucoanthocyanidin + 2-oxoglutarate + O2 = an anthocyanidin + succinate + CO2 + 2 H2O (overall reaction) (1a) a (2R,3S,4S)-leucoanthocyanidin + 2-oxoglutarate + O2 = a (4S)- 2,3-dehydroflavan-3,4-diol + succinate + CO2 + H2O (1b) a (4S)- 2,3-dehydroflavan-3,4-diol = an anthocyanidin + H2O |
||||||||||
For diagram of anthocyanin biosynthesis, click here | |||||||||||
Glossary: | taxifolin = 3,4-dihydroquercitin | ||||||||||
Other name(s): | leucocyanidin oxygenase; leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; ANS (gene name) | ||||||||||
Systematic name: | (2R,3S,4S)-leucoanthocyanidin,2-oxoglutarate:oxygen oxidoreductase | ||||||||||
Comments: | The enzyme requires iron(II) and ascorbate. It is involved in the pathway by which many flowering plants make anthocyanin flower pigments (glycosylated anthocyandins). The enzyme hydroxylates the C-3 carbon, followed by a trans diaxial elimination, forming a C-2,C-3 enol. The product loses a second water molecule to form anthocyanidins. When assayed in vitro, non-enzymic epimerization of the product can lead to formation of dihydroflavanols. Thus when the substrate is leucocyanidin, a mixture of (+)-taxifolin and (+)-epitaxifolin are formed. The enzyme can also oxidize the formed (+)-taxifolin to quercetin (cf. EC 1.14.20.6, flavonol synthase) [2,3]. | ||||||||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 180984-01-4 | ||||||||||
References: |
| ||||||||||