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Your query returned 1 entry. Printable version
EC | 1.14.99.58 | ||||||
Accepted name: | heme oxygenase (biliverdin-IX-β and δ-forming) | ||||||
Reaction: | (1) protoheme + 3 reduced acceptor + 3 O2 = biliverdin-IX-δ + CO + Fe2+ + 3 acceptor + 3 H2O (2) protoheme + 3 reduced acceptor + 3 O2 = biliverdin-IX-β + CO + Fe2+ + 3 acceptor + 3 H2O |
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For diagram of biliverdin biosynthesis, click here | |||||||
Glossary: | biliverdin-IX-β = 3,7-bis(2-carboxyethyl)-2,8,12,17-tetramethyl-13,18-divinylbilin-1,19(21H,24H)-dione biliverdin-IX-δ = 3,7-bis(2-carboxyethyl)-2,8,13,18-tetramethyl-12,17-divinylbilin-1,19(21H,24H)-dione |
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Other name(s): | pigA (gene name) | ||||||
Systematic name: | protoheme,donor:oxygen oxidoreductase (biliverdin-IX-β and δ-forming) | ||||||
Comments: | The enzyme, characterized from the bacterium Pseudomonas aeruginosa, differs from EC 1.14.15.20, heme oxygenase (biliverdin-producing, ferredoxin), in that the heme substrate is rotated by approximately 110 degrees within the active site, resulting in cleavage at a different part of the ring. It forms a mixture of about 70% biliverdin-IX-δ and 30% biliverdin-IX-β. | ||||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB | ||||||
References: |
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