EC |
1.2.1.33 |
Accepted name: |
(R)-dehydropantoate dehydrogenase |
Reaction: |
(R)-4-dehydropantoate + NAD+ + H2O = (R)-3,3-dimethylmalate + NADH + 2 H+ |
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For diagram of pantothenate catabolism, click here |
Other name(s): |
D-aldopantoate dehydrogenase; D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase |
Systematic name: |
(R)-4-dehydropantoate:NAD+ 4-oxidoreductase |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37250-96-7 |
References: |
1. |
Magee, P.T. and Snell, E.E. The bacterial degradation of pantothenic acid. IV. Enzymatic conversion of aldopantoate to α-ketoisovalerate. Biochemistry 5 (1966) 409–416. [PMID: 4287371] |
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[EC 1.2.1.33 created 1972] |
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