EC |
1.2.1.52 |
Accepted name: |
oxoglutarate dehydrogenase (NADP+) |
Reaction: |
2-oxoglutarate + CoA + NADP+ = succinyl-CoA + CO2 + NADPH |
Other name(s): |
oxoglutarate dehydrogenase (NADP) |
Systematic name: |
2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating) |
Comments: |
The Euglena enzyme can also use NAD+ as acceptor, but more slowly. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 126469-85-0 |
References: |
1. |
Inui, H., Miyatake, K., Nakano, Y. and Kitaoka, S. Occurrence of oxygen-sensitive, NADP +-dependent pyruvate dehydrogenase in mitochondria of Euglena gracilis. J. Biochem. (Tokyo) 96 (1984) 931–934. [PMID: 6438078] |
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[EC 1.2.1.52 created 1989] |
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