| EC |
1.2.1.60 |
| Accepted name: |
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |
| Reaction: |
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + 2 H+ |
| Other name(s): |
carboxymethylhydroxymuconic semialdehyde dehydrogenase |
| Systematic name: |
5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase |
| Comments: |
Involved in the tyrosine degradation pathway in Arthrobacter sp. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 63241-20-3 |
| References: |
| 1. |
Blakley, E.R. The catabolism of L-tyrosine by an Arthrobacter sp. Can. J. Microbiol. 23 (1977) 1128–1139. [PMID: 20216] |
| 2. |
Alonso, J.M. and Garrido-Pertierra, A. Carboxymethylhydroxymuconic semialdehyde dehydrogenase in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli. Biochim. Biophys. Acta 719 (1982) 165–167. [DOI] [PMID: 6756482] |
| 3. |
Cooper, R.A. and Skinner, M.A. Catabolism of 3- and 4-hydroxyphenylacetate by the 3,4-dihydroxyphenylacetate pathway in Escherichia coli. J. Bacteriol. 143 (1980) 302–306. [PMID: 6995433] |
| 4. |
Garrido-Pertierra, A. and Cooper, R.A. Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate pathway of Escherichia coli. Eur. J. Biochem. 117 (1981) 581–584. [DOI] [PMID: 7026235] |
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| [EC 1.2.1.60 created 2000] |
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