EC |
1.2.1.77 |
Accepted name: |
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) |
Reaction: |
3,4-didehydroadipyl-CoA semialdehyde + NADP+ + H2O = 3,4-didehydroadipyl-CoA + NADPH + H+ |
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For diagram of Benzoyl-CoA catabolism, click here |
Other name(s): |
BoxD; 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase |
Systematic name: |
3,4-didehydroadipyl-CoA semialdehyde:NADP+ oxidoreductase |
Comments: |
This enzyme catalyses a step in the aerobic benzoyl-coenzyme A catabolic pathway in Azoarcus evansii and Burkholderia xenovorans. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc |
References: |
1. |
Gescher, J., Ismail, W., Olgeschlager, E., Eisenreich, W., Worth, J. and Fuchs, G. Aerobic benzoyl-coenzyme A (CoA) catabolic pathway in Azoarcus evansii: conversion of ring cleavage product by 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase. J. Bacteriol. 188 (2006) 2919–2927. [DOI] [PMID: 16585753] |
2. |
Bains, J. and Boulanger, M.J. Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400. J. Mol. Biol. 379 (2008) 597–608. [DOI] [PMID: 18462753] |
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[EC 1.2.1.77 created 2010] |
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