EC |
1.2.1.89 |
Accepted name: |
D-glyceraldehyde dehydrogenase (NADP+) |
Reaction: |
D-glyceraldehyde + NADP+ + H2O = D-glycerate + NADPH + H+ |
Other name(s): |
glyceraldehyde dehydrogenase; GADH |
Systematic name: |
D-glyceraldehyde:NADP+ oxidoreductase |
Comments: |
The enzyme from the archaea Thermoplasma acidophilum and Picrophilus torridus is involved in the non-phosphorylative Entner-Doudoroff pathway. cf. EC 1.2.99.8, glyceraldehyde dehydrogenase (FAD-containing). |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
References: |
1. |
Jung, J.H. and Lee, S.B. Identification and characterization of Thermoplasma acidophilum glyceraldehyde dehydrogenase: a new class of NADP+-specific aldehyde dehydrogenase. Biochem. J. 397 (2006) 131–138. [DOI] [PMID: 16566751] |
2. |
Reher, M. and Schonheit, P. Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily. FEBS Lett. 580 (2006) 1198–1204. [DOI] [PMID: 16458304] |
|
[EC 1.2.1.89 created 2014] |
|
|
|
|