| EC |
1.2.1.96 |
| Accepted name: |
4-hydroxybenzaldehyde dehydrogenase (NADP+) |
| Reaction: |
4-hydroxybenzaldehyde + NADP+ + H2O = 4-hydroxybenzoate + NADPH + 2 H+ |
| Other name(s): |
p-hydroxybenzaldehyde dehydrogenase (ambiguous); pchA (gene name) |
| Systematic name: |
4-hydroxybenzaldehyde:NADP+ oxidoreductase |
| Comments: |
Involved in the aerobic pathway for degradation of toluene, 4-methylphenol, and 2,4-xylenol by several Pseudomonas strains. The enzyme is also active with 4-hydroxy-3-methylbenzaldehyde. cf. EC 1.2.1.64, 4-hydroxybenzaldehyde dehydrogenase (NAD+). |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, CAS registry number: 61229-72-9 |
| References: |
| 1. |
Whited, G.M. and Gibson, D.T. Separation and partial characterization of the enzymes of the toluene-4-monooxygenase catabolic pathway in Pseudomonas mendocina KR1. J. Bacteriol. 173 (1991) 3017–3020. [DOI] [PMID: 2019564] |
| 2. |
Chen, Y.F., Chao, H. and Zhou, N.Y. The catabolism of 2,4-xylenol and p-cresol share the enzymes for the oxidation of para-methyl group in Pseudomonas putida NCIMB 9866. Appl. Microbiol. Biotechnol. 98 (2014) 1349–1356. [DOI] [PMID: 23736872] |
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| [EC 1.2.1.96 created 2015] |
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