| EC |
1.20.1.1 |
| Accepted name: |
phosphonate dehydrogenase |
| Reaction: |
phosphonate + NAD+ + H2O = phosphate + NADH + H+ |
| Other name(s): |
NAD:phosphite oxidoreductase; phosphite dehydrogenase |
| Systematic name: |
phosphonate:NAD+ oxidoreductase |
| Comments: |
NADP+ is a poor substitute for NAD+ in the enzyme from Pseudomonas stutzeri WM88. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9031-35-0 |
| References: |
| 1. |
Costas, A.M.G., White, A.K. and Metcalf, W.W. Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88. J. Biol. Chem. 276 (2001) 17429–17436. [DOI] [PMID: 11278981] |
| 2. |
Vrtis, J.M., White, A.K., Metcalf, W.W. and van der Donk, W.A. Phosphite dehydrogenase: An unusual phosphoryl transfer reaction. J. Am. Chem. Soc. 123 (2001) 2672–2673. [PMID: 11456941] |
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| [EC 1.20.1.1 created 2001] |
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