The Enzyme Database

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Accepted name: geissoschizine dehydrogenase
Reaction: geissoschizine + NADP+ = 4,21-didehydrogeissoschizine + NADPH
For diagram of geissoschizine and sarpagine biosynthesis, click here
Systematic name: geissoschizine:NADP+ 4,21-oxidoreductase
Comments: Involved in the interconversion of heteroyohimbine alkaloids in Catharanthus roseus.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 84399-94-0
1.  Pfitzner, A. and Stöckigt, J. Partial-purification and characterization of geissoschizine dehydrogenase from suspension-cultures of Catharanthus roseus. Phytochemistry 21 (1982) 1585–1588.
[EC created 1986]

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