ExplorEnz: EC 1.3.1.87

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1.3.1.87

Accepted name:

3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase

Reaction:

(1) 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD⁺ = 3-(2,3-dihydroxyphenyl)propanoate + NADH + H⁺
(2) (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD⁺ = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NADH + H⁺

For diagram of 3-phenylpropanoate catabolism, click here and for diagram of cinnamate catabolism, click here

Glossary:

(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate = trans-2,3-dihydroxycinnamate

Other name(s):

hcaB (gene name); cis-dihydrodiol dehydrogenase; 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase

Systematic name:

3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate:NAD⁺ oxidoreductase

Comments:

This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation.

Links to other databases:

BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc

References:

1.	Díaz, E., Ferrández, A. and García, J.L. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. J. Bacteriol. 180 (1998) 2915–2923. [PMID: 9603882]

[EC 1.3.1.87 created 2011]