ExplorEnz: EC 1.3.99.25

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1.3.99.25

Accepted name:

carvone reductase

Reaction:

(1) (+)-dihydrocarvone + acceptor = (–)-carvone + reduced acceptor
(2) (–)-isodihydrocarvone + acceptor = (+)-carvone + reduced acceptor

For diagram of (–)-carvone catabolism, click here

Glossary:

(+)-dihydrocarvone = (1S,4R)-menth-8-en-2-one
(+)-isodihydrocarvone = (1S,4R)-menth-8-en-2-one
(–)-carvone = (4R)-mentha-1(6),8-dien-6-one = (5R)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one

Systematic name:

(+)-dihydrocarvone:acceptor 1,6-oxidoreductase

Comments:

This enzyme participates in the carveol and dihydrocarveol degradation pathway of the Gram-positive bacterium Rhodococcus erythropolis DCL14. The enzyme has not been purified, and requires an unknown cofactor, which is different from NAD⁺, NADP⁺ or a flavin.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	van der Werf, M.J. and Boot, A.M. Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14. Microbiology 146 (2000) 1129–1141. [DOI] [PMID: 10832640]

[EC 1.3.99.25 created 2008]