The Enzyme Database

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Accepted name: valine dehydrogenase (NAD+)
Reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH + H+
Systematic name: L-valine:NAD+ oxidoreductase (deaminating)
Comments: The enzyme from Streptomyces spp. has no activity with NADP+ [cf. EC, valine dehydrogenase (NADP+)].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Vancurová, I., Vancura, A., Volc, J., Neuzil, J., Flieger, M., Basarová, G. and Behal, V. Isolation and characterization of valine dehydrogenase from Streptomyces aureofaciens. J. Bacteriol. 170 (1988) 5192–5196. [DOI] [PMID: 3182727]
2.  Navarrete, R.M., Vara, J.A. and Hutchinson, C.R. Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2). J. Gen. Microbiol. 136 (1990) 273–281. [DOI] [PMID: 2324704]
[EC created 2012]

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