| EC |
1.5.1.30 |
| Accepted name: |
flavin reductase (NADPH) |
| Reaction: |
reduced riboflavin + NADP+ = riboflavin + NADPH + H+ |
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For diagram of riboflavin biosynthesis (late stages), click here |
| Other name(s): |
NADPH:flavin oxidoreductase; riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase; flavin mononucleotide reductase; flavine mononucleotide reductase; FMN reductase (NADPH); NADPH-dependent FMN reductase; NADPH-flavin reductase; NADPH-FMN reductase; NADPH-specific FMN reductase; riboflavin mononucleotide reductase; riboflavine mononucleotide reductase; NADPH2 dehydrogenase (flavin); NADPH2:riboflavin oxidoreductase |
| Systematic name: |
reduced-riboflavin:NADP+ oxidoreductase |
| Comments: |
The enzyme reduces riboflavin, and, less efficiently, FMN and FAD. NADH is oxidized less efficiently than NADPH. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 56626-29-0 |
| References: |
| 1. |
Yubisui, T., Tamura, M. and Takeshita, M. Characterization of a second form of NADPH-flavin reductase purified from human erythrocytes. Biochem. Int. 15 (1987) 1–8. [PMID: 3453680] |
| 2. |
Cunningham, O., Gore, M.G. and Mantle, T.J. Initial-rate kinetics of the flavin reductase reaction catalysed by human biliverdin-IXβ reductase (BVR-B). Biochem. J. 345 (2000) 393–399. [PMID: 10620517] |
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| [EC 1.5.1.30 created 1982 as EC 1.6.8.2, transferred 2002 to EC 1.5.1.30, modified 2011] |
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