| EC |
1.5.1.40 |
| Accepted name: |
8-hydroxy-5-deazaflavin:NADPH oxidoreductase |
| Reaction: |
reduced coenzyme F420 + NADP+ = oxidized coenzyme F420 + NADPH + H+ |
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For diagram of coenzyme F420 biosynthesis, click here |
| Other name(s): |
8-OH-5dFl:NADPH oxidoreductase |
| Systematic name: |
reduced coenzyme F420:NADP+ oxidoreductase |
| Comments: |
The enzyme has an absolute requirement for both the 5-deazaflavin structure and the presence of an 8-hydroxy group in the substrate [1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Eker, A.P., Hessels, J.K. and Meerwaldt, R. Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus. Biochim. Biophys. Acta 990 (1989) 80–86. [DOI] [PMID: 2492438] |
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| [EC 1.5.1.40 created 2011] |
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