The Enzyme Database

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Accepted name: formyltetrahydrofolate dehydrogenase
Reaction: 10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+
For diagram of folate cofactors, click here and for diagram of C1 metabolism, click here
Other name(s): 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase; 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase
Systematic name: 10-formyltetrahydrofolate:NADP+ oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37256-25-0
1.  Kutzbach, C. and Stokstad, E.L.R. Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver. Biochem. Biophys. Res. Commun. 30 (1968) 111–117. [DOI] [PMID: 4384443]
[EC created 1972]

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