| EC |
1.6.5.12 |
| Accepted name: |
demethylphylloquinone reductase |
| Reaction: |
demethylphylloquinone + NADPH + H+ = demethylphylloquinol + NADP+ |
| Glossary: |
demethylphylloquinone = 2-phytyl-1,4-naphthoquinone |
| Other name(s): |
ndbB (gene name); NDC1 (gene name); demethylphylloquinone:NADPH oxidoreductase |
| Systematic name: |
NADPH:demethylphylloquinone oxidoreductase |
| Comments: |
The enzyme, found in plants and cyanobacteria, is involved in the biosynthesis of phylloquinone (vitamin K1), an electron carrier associated with photosystem I. The enzyme is a type II NADPH dehydrogenase and requires a flavine adenine dinucleotide cofactor. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Fatihi, A., Latimer, S., Schmollinger, S., Block, A., Dussault, P.H., Vermaas, W.F., Merchant, S.S. and Basset, G.J. A dedicated type II NADPH dehydrogenase performs the penultimate step in the biosynthesis of vitamin K1 in Synechocystis and Arabidopsis. Plant Cell 27 (2015) 1730–1741. [DOI] [PMID: 26023160] |
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| [EC 1.6.5.12 created 2015] |
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