The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: nitroquinoline-N-oxide reductase
Reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+
Other name(s): 4-nitroquinoline 1-oxide reductase; 4NQO reductase; NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase
Systematic name: 4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 37256-35-2
1.  Toriyama, N. [Metabolism of quinoline derivatives. On the reducing enzyme of 4-nitroquinoline-N-oxide] Nichidai Igaku Zasshi 24 (1965) 423–432. (in Japanese)
2.  Stanley, J.S., York, J.L. and Benson, A.M. Nitroreductases and glutathione transferases that act on 4-nitroquinoline 1-oxide and their differential induction by butylated hydroxyanisole in mice. Cancer Res. 52 (1992) 58–63. [PMID: 1370076]
[EC created 1972 as EC, transferred 2002 to EC]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald