| EC |
1.8.1.15 |
| Accepted name: |
mycothione reductase |
| Reaction: |
2 mycothiol + NAD(P)+ = mycothione + NAD(P)H + H+ |
| Glossary: |
mycothiol = 1-O-[2-(N2-acetyl-L-cysteinamido)-2-deoxy--D-glucopyranosyl]-1D-myo-inositol
mycothione = oxidized (disulfide) form of mycothiol |
| Other name(s): |
mycothiol-disulfide reductase |
| Systematic name: |
mycothiol:NAD(P)+ oxidoreductase |
| Comments: |
Contains FAD. No activity with glutathione, trypanothione or coenzyme A as substrate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 252212-92-3 |
| References: |
| 1. |
Patel, M.P. and Blanchard, J.S. Expression, purification, and characterization of Mycobacterium tuberculosis mycothione reductase. Biochemistry 38 (1999) 11827–11833. [DOI] [PMID: 10512639] |
| 2. |
Patel, M.P. and Blanchard, J.S. Mycobacterium tuberculosis mycothione reductase: pH dependence of the kinetic parameters and kinetic isotope effects. Biochemistry 40 (2001) 5119–5126. [DOI] [PMID: 11318633] |
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| [EC 1.8.1.15 created 2002] |
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