| EC |
1.8.1.20 |
| Accepted name: |
4,4′-dithiodibutanoate disulfide reductase |
| Reaction: |
2 4-sulfanylbutanoate + NAD+ = 4,4′-disulfanediyldibutanoate + NADH + H+ |
| Systematic name: |
4-sulfanylbutanoate:NAD+ oxidoreductase |
| Comments: |
The enzyme, characterized from the bacterium Rhodococcus erythropolis MI2, contains an FMN cofator. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
| References: |
| 1. |
Khairy, H., Wubbeler, J.H. and Steinbuchel, A. Biodegradation of the organic disulfide 4,4′-dithiodibutyric acid by Rhodococcus spp. Appl. Environ. Microbiol. 81 (2015) 8294–8306. [DOI] [PMID: 26407888] |
| 2. |
Khairy, H., Wubbeler, J.H. and Steinbuchel, A. The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4′-dithiodibutyric acid degradation. Lett. Appl. Microbiol. 63 (2016) 434–441. [DOI] [PMID: 27564089] |
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| [EC 1.8.1.20 created 2017] |
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