| EC |
1.8.2.7 |
| Accepted name: |
thiocyanate desulfurase |
| Reaction: |
thiocyanate + 2 ferricytochrome c + H2O = cyanate + sulfur + 2 ferrocytochrome c + 2 H+ |
| Other name(s): |
TcDH; thiocyanate dehydrogenase |
| Systematic name: |
thiocyanate:cytochrome c oxidoreductase (cyanate and sulfur-forming) |
| Comments: |
The enzyme, characterized from the haloalkaliphilic sulfur-oxidizing bacterium Thioalkalivibrio paradoxus, contains three copper ions in its active site. It catalyses the direct conversion of thiocyanate into cyanate and elemental sulfur without involvement of molecular oxygen. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Tikhonova, T.V., Sorokin, D.Y., Hagen, W.R., Khrenova, M.G., Muyzer, G., Rakitina, T.V., Shabalin, I.G., Trofimov, A.A., Tsallagov, S.I. and Popov, V.O. Trinuclear copper biocatalytic center forms an active site of thiocyanate dehydrogenase. Proc. Natl. Acad. Sci. USA (2020) . [PMID: 32094184] |
|
| [EC 1.8.2.7 created 2020] |
| |
|
| |
|
Printable version